Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | KDM5A | P29375 | 4/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095105 | 0.82 | MAPK14 (0.46) | KDM4CMAPK14GSK3BMAPK13GCGR | |
| SCHEMBL16094728 | 0.81 | KDM4C (0.64) | KDM4CMAPK14GSK3BKDM5AKDM5B | |
| SCHEMBL16094974 | 0.79 | KDM4C (0.56) | KDM4CMAPK14GSK3BKDM5AKDM5B | |
| SCHEMBL16034492 | 0.76 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16033932 | 0.74 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16095914 | 0.74 | MAPK14 (0.50) | KDM4CMAPK14GSK3BMAPK13GCGR | |
| SCHEMBL16095177 | 0.74 | KDM4C (0.39) | KDM4CMAPK14GSK3BMAPK13GCGR | |
| SCHEMBL16094861 | 0.73 | KDM4C (0.62) | KDM4CMAPK14GSK3BKDM5AKDM5B | |
| SCHEMBL16095092 | 0.73 | KDM4C (0.63) | KDM4CKDM5AKDM5B | |
| SCHEMBL16095505 | 0.73 | KDM4C (0.56) | KDM4CMAPK14GSK3BKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |