Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095105 | 0.92 | MAPK14 (0.46) | KDM4CPHF8MAPK14MAPK13MAPK12 | |
| SCHEMBL16095836 | 0.85 | PHF8 (0.39) | KDM4CPHF8MAPK14LMNAPOLB | |
| SCHEMBL16095914 | 0.84 | MAPK14 (0.50) | KDM4CMAPK14MAPTMAPK13MAPK12 | |
| SCHEMBL16095191 | 0.80 | MAPK14 (0.39) | KDM4CMAPK14IDH1MAPK13MAPK12 | |
| SCHEMBL16095092 | 0.79 | KDM4C (0.63) | KDM4CKDM2B | |
| SCHEMBL16095066 | 0.77 | PHF8 (0.41) | KDM4CPHF8LMNAPOLBMAPT | |
| SCHEMBL16095603 | 0.75 | LMNA (0.38) | KDM4CPHF8MAPK14LMNAPOLB | |
| SCHEMBL16032963 | 0.74 | KDM4C (0.64) | KDM4CKDM2BPHF8 | |
| SCHEMBL16094879 | 0.74 | KDM4C (0.61) | KDM4CMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL16094728 | 0.72 | KDM4C (0.64) | KDM4CKDM2BMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |