Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.47 |
| ▸ | KDM5A | P29375 | 3/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CDH1 | P12830 | 1/20 | 0.38 |
| ▸ | APC | P25054 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094974 | 0.90 | KDM4C (0.56) | KDM4CKDM5BKDM5AKDM2BKDM4A | |
| SCHEMBL16095191 | 0.80 | MAPK14 (0.39) | KDM4CGSK3BMAPK14 | |
| SCHEMBL16095315 | 0.79 | KDM4C (0.60) | KDM4CKDM5BKDM5AKDM2BKDM4A | |
| SCHEMBL16094879 | 0.73 | KDM4C (0.61) | KDM4CKDM5BKDM5AKMOKDM4A | |
| SCHEMBL16033766 | 0.72 | KDM4C (1.00) | KDM4CKDM5BKDM5AKDM2BKDM4A | |
| SCHEMBL31301524 | 0.72 | KMO (0.71) | KDM4CKDM5BKDM5AKDM2BKMO | |
| SCHEMBL16095312 | 0.72 | KDM4C (0.60) | KDM4CKDM5BKDM5AKDM2BKMO | |
| SCHEMBL16094741 | 0.70 | MAPK14 (0.48) | GSK3BMAPK14 | |
| SCHEMBL16096065 | 0.69 | KDM4C (0.60) | KDM4CKDM5BKDM5AKDM2BKDM4A | |
| SCHEMBL16095834 | 0.68 | KDM4C (0.56) | KDM4CKDM5BKDM5AKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |