Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100266 | 0.87 | IDH1 (0.36) | HRH3CDC7DBF4NPY5RKCNH2 | |
| SCHEMBL17604615 | 0.87 | NPY5R (0.44) | HRH3NPY5RKCNH2 | |
| SCHEMBL16095290 | 0.84 | DYRK1A (0.40) | KDM4C | |
| SCHEMBL16095455 | 0.80 | CYP19A1 (0.38) | HRH3NPY5RKCNH2KDM4C | |
| SCHEMBL16100476 | 0.79 | MAPK14 (0.41) | HRH3CDC7DBF4NPY5RKCNH2 | |
| SCHEMBL17604548 | 0.78 | NPY5R (0.38) | HRH3CDC7DBF4NPY5RKCNH2 | |
| SCHEMBL16094947 | 0.74 | KDM4C (0.45) | KDM4C | |
| SCHEMBL16095481 | 0.74 | KDM4C (0.57) | KDM4C | |
| SCHEMBL16095353 | 0.72 | NPY5R (0.35) | NPY5RKCNH2KDM4C | |
| SCHEMBL16033875 | 0.71 | NPY5R (0.38) | CDC7DBF4NPY5RKCNH2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |