Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094947 | 0.89 | KDM4C (0.45) | KDM4CMRGPRX4FNTAFNTBPGGT1B | |
| SCHEMBL16095270 | 0.80 | KDM4C (0.44) | KDM4CPPIACTSSMAOBPTGER1 | |
| SCHEMBL16100266 | 0.79 | IDH1 (0.36) | KDM4CCTSSMAOB | |
| SCHEMBL16100476 | 0.77 | MAPK14 (0.41) | — | |
| SCHEMBL17604615 | 0.75 | NPY5R (0.44) | — | |
| SCHEMBL16095290 | 0.74 | DYRK1A (0.40) | KDM4CMAOB | |
| SCHEMBL16094914 | 0.74 | HRH3 (0.36) | KDM4C | |
| SCHEMBL16095479 | 0.74 | KDM4C (0.65) | KDM4CMRGPRX4MGAMGAASI | |
| SCHEMBL16095455 | 0.73 | CYP19A1 (0.38) | KDM4C | |
| SCHEMBL16034105 | 0.73 | KDM4C (1.00) | KDM4CMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |