Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100266 | 0.88 | IDH1 (0.36) | NPY5RKCNH2VNN1HRH3 | |
| SCHEMBL16100476 | 0.87 | MAPK14 (0.41) | NPY5RKCNH2MAPK14HRH3 | |
| SCHEMBL16094914 | 0.87 | HRH3 (0.36) | NPY5RKCNH2HRH3 | |
| SCHEMBL16095455 | 0.85 | CYP19A1 (0.38) | NPY5RKCNH2MAPK14HRH3 | |
| SCHEMBL16095290 | 0.85 | DYRK1A (0.40) | MAPK14VNN1 | |
| SCHEMBL16094947 | 0.79 | KDM4C (0.45) | MAPK14 | |
| SCHEMBL17604548 | 0.79 | NPY5R (0.38) | NPY5RKCNH2HRH3 | |
| SCHEMBL16095270 | 0.79 | KDM4C (0.44) | NPY5RKCNH2MAPK14 | |
| SCHEMBL16095353 | 0.78 | NPY5R (0.35) | NPY5RKCNH2 | |
| SCHEMBL16102462 | 0.77 | NPY5R (0.38) | NPY5RKCNH2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |