Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604615 | 0.78 | NPY5R (0.44) | NPY5RKCNH2 | |
| SCHEMBL16095455 | 0.77 | CYP19A1 (0.38) | NPY5RKCNH2KCNK3KDM4C | |
| SCHEMBL16095270 | 0.77 | KDM4C (0.44) | NPY5RKCNH2KCNK3KDM4C | |
| SCHEMBL16100476 | 0.77 | MAPK14 (0.41) | NPY5RKCNH2 | |
| SCHEMBL16094947 | 0.76 | KDM4C (0.45) | KDM4C | |
| SCHEMBL16100266 | 0.75 | IDH1 (0.36) | NPY5RKCNH2KDM4CLMNA | |
| SCHEMBL16102462 | 0.74 | NPY5R (0.38) | NPY5RKCNH2KCNK3KDM4CHPGD | |
| SCHEMBL17604548 | 0.74 | NPY5R (0.38) | NPY5RKCNH2KDM4C | |
| SCHEMBL16094914 | 0.72 | HRH3 (0.36) | NPY5RKCNH2KDM4C | |
| SCHEMBL16095290 | 0.70 | DYRK1A (0.40) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |