Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095479 | 0.89 | KDM4C (0.65) | KDM4CMAPK14XDHPIK3CDABL1 | |
| SCHEMBL16095268 | 0.84 | KDM4C (0.45) | KDM4CMAPK14 | |
| SCHEMBL16095526 | 0.81 | KDM4C (0.69) | KDM4C | |
| SCHEMBL16095454 | 0.80 | MAPK14 (0.41) | KDM4CMAPK14TGFBR1MAPK13MAPK12 | |
| SCHEMBL16033837 | 0.79 | KDM4C (0.80) | KDM4C | |
| SCHEMBL17604614 | 0.78 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL16094947 | 0.74 | KDM4C (0.45) | KDM4CMAPK14 | |
| SCHEMBL16095288 | 0.74 | KMT2A (0.43) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL16094913 | 0.73 | MAPK14 (0.39) | KDM4CMAPK14TGFBR1MAPK13MAPK12 | |
| SCHEMBL20302267 | 0.71 | MAOB (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |