Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094913 | 0.87 | MAPK14 (0.39) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL16095288 | 0.86 | KMT2A (0.43) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL16095454 | 0.85 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL16095120 | 0.82 | KDM4C (0.41) | MAPK14GSK3BNPY5RKCNH2 | |
| SCHEMBL16095224 | 0.81 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL16094741 | 0.79 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL16094945 | 0.78 | KDM4C (0.51) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL16102461 | 0.77 | KDM4C (0.42) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL15104626 | 0.77 | NPY5R (0.53) | MAPK14GCGRNPY5RKCNH2 | |
| SCHEMBL17604545 | 0.77 | NPY5R (0.37) | NPY5RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |