Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | GSK3B | P49841 | 5/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604614 | 0.85 | MAPK14 (0.46) | MAPK14GSK3BNPY5RKCNH2MAPK13 | |
| SCHEMBL16094913 | 0.80 | MAPK14 (0.39) | MAPK14GSK3BTGFBR1KDM4CTGFBR2 | |
| SCHEMBL16094945 | 0.80 | KDM4C (0.51) | MAPK14TGFBR1KDM4CMAPK13MAPK12 | |
| SCHEMBL16095288 | 0.79 | KMT2A (0.43) | MAPK14GSK3BMAPK13ALOX5GCGR | |
| SCHEMBL16095120 | 0.75 | KDM4C (0.41) | MAPK14GSK3BKDM4CNPY5RKCNH2 | |
| SCHEMBL16033412 | 0.75 | KDM4C (0.61) | KDM4C | |
| SCHEMBL17604545 | 0.72 | NPY5R (0.37) | KDM4CNPY5RKCNH2 | |
| SCHEMBL16095479 | 0.72 | KDM4C (0.65) | MAPK14KDM4C | |
| SCHEMBL16102461 | 0.69 | KDM4C (0.42) | MAPK14KDM4CNPY5RKCNH2MAPK13 | |
| SCHEMBL16095268 | 0.68 | KDM4C (0.45) | MAPK14KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |