Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.66 |
| ▸ | KDM4A | O75164 | 5/20 | 0.59 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.59 |
| ▸ | KDM5A | P29375 | 8/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095327 | 0.89 | KDM4C (0.66) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16035034 | 0.79 | KDM4C (1.00) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16033490 | 0.74 | KDM4C (1.00) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL20978722 | 0.73 | KDM4C (0.68) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16104961 | 0.73 | KDM5B (0.55) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16095331 | 0.72 | KDM2B (0.55) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16095592 | 0.72 | KDM4C (0.42) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16094674 | 0.71 | KDM4C (0.48) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16094676 | 0.71 | KDM5A (0.49) | KDM4CKDM4AKDM2BKDM5AKDM5B | |
| SCHEMBL16094521 | 0.70 | KDM5B (0.59) | KDM4CKDM4AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |