Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095379 | 0.83 | KDM4C (0.47) | PHF8KDM4CKDM5BKDM4BKDM5C | |
| SCHEMBL16095566 | 0.82 | KDM4C (0.61) | PHF8KDM4CKDM4AKDM5BKDM4B | |
| SCHEMBL16095150 | 0.80 | PHF8 (0.41) | PHF8KDM4CTSHRMAPK1KDM2B | |
| SCHEMBL16034010 | 0.77 | KDM4C (0.68) | PHF8KDM4CKDM4AKDM5BKDM2B | |
| SCHEMBL16094975 | 0.76 | KDM4C (0.43) | PHF8KDM4CKDM4AKDM5BKDM4B | |
| SCHEMBL16095193 | 0.76 | KDM4C (0.59) | KDM4CKDM4AKDM5BKDM4BKDM5C | |
| SCHEMBL16094521 | 0.74 | KDM5B (0.59) | KDM4CKDM4AKDM5BKDM4BKDM5C | |
| SCHEMBL16094800 | 0.73 | KDM4C (0.61) | PHF8KDM4CKDM4AKDM5BKDM4B | |
| SCHEMBL17604563 | 0.72 | KDM5B (0.41) | PHF8KDM4CKDM5BKDM4BKDM5C | |
| SCHEMBL16095026 | 0.72 | KDM5C (0.47) | KDM4CKDM4AKDM5BKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |