Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.47 |
| ▸ | KDM5A | P29375 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094975 | 0.90 | KDM4C (0.43) | KDM4CKDM5BKDM5AP2RX7KDM4B | |
| SCHEMBL17604563 | 0.84 | KDM5B (0.41) | KDM4CKDM5BKDM5AKDM4BKDM5C | |
| SCHEMBL16095274 | 0.83 | PHF8 (0.42) | KDM4CKDM5BKDM5AKDM4BKDM5C | |
| SCHEMBL17604506 | 0.80 | KDM4C (0.54) | KDM4CKDM5BKDM5AKDM4BKDM5C | |
| SCHEMBL16095346 | 0.79 | KDM4C (0.52) | KDM4CKDM5BKDM5AP2RX7KDM4B | |
| SCHEMBL16095066 | 0.78 | PHF8 (0.41) | KDM4CKDM5BKDM5APHF8KDM2A | |
| SCHEMBL16094521 | 0.77 | KDM5B (0.59) | KDM4CKDM5BKDM5AKDM4BKDM5C | |
| SCHEMBL16095193 | 0.77 | KDM4C (0.59) | KDM4CKDM5BKDM5AKDM4BKDM5C | |
| SCHEMBL16095181 | 0.76 | KDM5B (0.44) | KDM4CKDM5BKDM4BKDM5CMAP4K4 | |
| SCHEMBL1568225 | 0.76 | KDM4C (0.46) | KDM4CKDM5BKDM5AP2RX7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |