Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.59 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095598 | 0.85 | KDM4C (0.56) | KDM4CKDM5AKDM2BKDM5BPDE4D | |
| SCHEMBL16095350 | 0.76 | KDM4C (0.67) | KDM4CKDM5AKDM2BKDM5BPDE4D | |
| SCHEMBL16034055 | 0.74 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16095313 | 0.71 | KDM4C (0.52) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL17604537 | 0.70 | KDM4C (0.40) | KDM4CKDM5AKDM2BPDE4DKMO | |
| SCHEMBL17604578 | 0.70 | KDM4C (0.40) | KDM4CKDM5AKDM2BPDE4DKMO | |
| SCHEMBL16095596 | 0.70 | KDM4C (0.65) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16095794 | 0.68 | KDM4C (0.52) | KDM4CKDM5AKDM2BKDM5BMRGPRX4 | |
| SCHEMBL16034821 | 0.67 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16034238 | 0.67 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |