Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.67 |
| ▸ | KDM5A | P29375 | 3/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.38 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095596 | 0.86 | KDM4C (0.65) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16034055 | 0.80 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16095351 | 0.76 | KDM4C (0.59) | KDM4CKDM5AKDM2BKDM5BPDE4D | |
| SCHEMBL17604576 | 0.71 | KDM4C (0.47) | KDM4CKDM5AKDM2BMAPK14GSK3B | |
| SCHEMBL16095312 | 0.70 | KDM4C (0.60) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL17604535 | 0.70 | KDM4C (0.46) | KDM4CKDM5AKDM2BMAPK14GSK3B | |
| SCHEMBL16034821 | 0.69 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16034238 | 0.69 | KDM4C (1.00) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16095598 | 0.69 | KDM4C (0.56) | KDM4CKDM5AKDM2BKDM5BPDE4D | |
| SCHEMBL16094991 | 0.68 | KDM4C (0.60) | KDM4CKDM5AKDM2BKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |