Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611671 | 1.00 | PDE5A (0.39) | PDE5ATLR8ACHEAMY1AHTT | |
| SCHEMBL1611182 | 0.98 | PDE5A (0.40) | PDE5ATLR8ACHEAMY1AALDH1A1 | |
| SCHEMBL1610292 | 0.93 | PDE5A (0.44) | PDE5ATLR8ACHEAMY1AALDH1A1 | |
| SCHEMBL1611849 | 0.86 | ALDH1A1 (0.43) | PDE5ATLR8ACHEHTTCNR1 | |
| SCHEMBL1610680 | 0.86 | ALDH1A1 (0.43) | PDE5ATLR8ACHEHTTCNR1 | |
| SCHEMBL1609490 | 0.85 | AMY1A (0.40) | PDE5AAMY1AHTTALDH1A1KDM4E | |
| SCHEMBL11649550 | 0.84 | AMY1A (0.35) | PDE5AAMY1AALDH1A1KDM4ELMNA | |
| SCHEMBL1610402 | 0.84 | ALDH1A1 (0.43) | PDE5ATLR8HTTCNR1CNR2 | |
| SCHEMBL9233272 | 0.83 | PDE5A (0.40) | PDE5AHTTCNR1CNR2ALDH1A1 | |
| SCHEMBL5480187 | 0.82 | AMY1A (0.36) | PDE5AAMY1AHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110087034-A1 | Organic Semiconductor Material | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2248818-A1 | ORGANIC SEMICONDUCTOR MATERIAL | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110087034-A1 | Organic Semiconductor Material | OR10J3, TST, OR51E2 | PDE5A 3568/4885TLR8 4323/4885ACHE 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.