Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102462 | 0.84 | NPY5R (0.38) | KDM4CCTSSMAPK14KCNH2NPY5R | |
| SCHEMBL16094947 | 0.84 | KDM4C (0.45) | KDM4CPPIACTSSMAPK14PTGER1 | |
| SCHEMBL16095481 | 0.80 | KDM4C (0.57) | KDM4CPPIACTSSPTGER1MAOB | |
| SCHEMBL16100476 | 0.80 | MAPK14 (0.41) | MAPK14KCNH2NPY5R | |
| SCHEMBL16095141 | 0.80 | KDM4C (0.61) | KDM4C | |
| SCHEMBL17604615 | 0.79 | NPY5R (0.44) | MAPK14KCNH2NPY5R | |
| SCHEMBL16095353 | 0.77 | NPY5R (0.35) | KDM4CKCNH2NPY5RKCNK3 | |
| SCHEMBL16095268 | 0.73 | KDM4C (0.45) | KDM4CPPIAMAPK14CCNT1CCNA2 | |
| SCHEMBL16034902 | 0.72 | KDM4C (0.66) | KDM4CMAPK14CCNT1CCNA2CDK2 | |
| SCHEMBL17604578 | 0.72 | KDM4C (0.40) | KDM4CCCNA2CDK2CCNA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |