Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782163 | 0.86 | MEN1 (0.46) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL5005582 | 0.83 | MAPT (0.63) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL22291692 | 0.81 | MAPT (0.69) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL22389455 | 0.76 | MAPT (0.61) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL21677327 | 0.76 | MAPT (0.51) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL21677249 | 0.75 | MAPT (0.50) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL6677275 | 0.75 | MAPT (0.73) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL18972415 | 0.75 | MAPT (0.56) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL14334021 | 0.75 | MAPT (0.56) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL1667912 | 0.74 | ALDH1A1 (0.56) | ALDH1A1RAB9AKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970365-A1 | PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS | Ibis Biosciences, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150845-A1 | PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS | IBIS BIOSCIENCES, INC. (US) | 2014-09-25 | — | — | WO | disclosed |