Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624163 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDCA12POLB | |
| SCHEMBL20427994 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL1691854 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDCA12POLB | |
| SCHEMBL30331149 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL2581176 | 0.81 | CA12 (0.52) | ALDH1A1TSHRCA12POLBCYP2C19 | |
| SCHEMBL1667872 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDCA12POLB | |
| SCHEMBL31331797 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL28839073 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL1665240 | 0.78 | PDK1 (0.40) | ALDH1A1TSHRCYP2C19HTTNPSR1 | |
| SCHEMBL3932156 | 0.78 | POLB (0.50) | ALDH1A1TSHRHPGDPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |