Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611399 | 0.92 | KDM4C (0.47) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13769165 | 0.90 | PDE10A (0.40) | MAPTCYP3A4CYP2D6ALDH1A1HPGD | |
| SCHEMBL12712820 | 0.90 | PDE10A (0.40) | MAPTCYP3A4CYP2D6KDM4CHPGD | |
| SCHEMBL1610305 | 0.87 | PDE10A (0.44) | MAPTALDH1A1HSD17B10HIF1AHPGD | |
| SCHEMBL2683023 | 0.86 | KDM4C (0.49) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1610899 | 0.85 | PDE10A (0.48) | MAPTALDH1A1RAB9A | |
| SCHEMBL12737605 | 0.83 | APLNR (0.44) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1609110 | 0.83 | HPGD (0.50) | ALDH1A1HSD17B10HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL13769408 | 0.82 | PDE10A (0.44) | CYP3A4CYP2D6ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL13769420 | 0.82 | MTNR1A (0.41) | MAPTALDH1A1TDP1KDM4CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | MAPT 2800/4885MEN1 3860/4885KMT2A 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.