Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499740 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2BSIGMAR1KCNH2HRH3 | |
| SCHEMBL28039851 | 0.87 | SIGMAR1 (0.46) | SIGMAR1KCNH2HRH3METTAAR1 | |
| SCHEMBL16097900 | 0.87 | MET (0.37) | GRIN1GRIN2BHPGDMET | |
| SCHEMBL16097902 | 0.87 | MET (0.37) | GRIN1GRIN2BHPGDMET | |
| SCHEMBL16095645 | 0.78 | GRIN1 (0.46) | GRIN1GRIN2BALDH1A1HPGDMEN1 | |
| SCHEMBL16095643 | 0.78 | GRIN1 (0.46) | GRIN1GRIN2BALDH1A1HPGDMEN1 | |
| SCHEMBL17499339 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1GAAMAPT | |
| SCHEMBL17499337 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1GAAMAPT | |
| SCHEMBL16098403 | 0.76 | GRIN1 (0.50) | GRIN1GRIN2BALDH1A1HPGDMEN1 | |
| SCHEMBL16098404 | 0.76 | GRIN1 (0.50) | GRIN1GRIN2BALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |