Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156624 | 0.81 | TSHR (0.35) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL6156621 | 0.78 | TSHR (0.33) | TSHRALDH1A1GLAMAPTCRHBP | |
| SCHEMBL1257089 | 0.76 | TSHR (0.43) | TSHRALDH1A1GLAMAPTCHRM2 | |
| SCHEMBL1258403 | 0.74 | TSHR (0.42) | TSHRALDH1A1GLAMAPTCHRM2 | |
| SCHEMBL1101358 | 0.72 | L3MBTL1 (0.41) | TSHRALDH1A1GLAMAPTCHRM2 | |
| SCHEMBL14058643 | 0.69 | TSHR (0.38) | TSHRALDH1A1GLACHRM2HTR1A | |
| SCHEMBL2855665 | 0.69 | MEN1 (0.48) | TSHRALDH1A1GLANPSR1KCNH2 | |
| Hydrochloric Acid SCHEMBL4555833 | 0.68 | TSHR (0.41) | TSHRALDH1A1GLAMAPTCHRM2 | |
| SCHEMBL2911078 | 0.68 | LTA4H (0.44) | TSHRALDH1A1GLAMAPTCRHBP | |
| Hydrochloric Acid SCHEMBL28613980 | 0.68 | ALDH1A1 (0.37) | TSHRALDH1A1GLACHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |