Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | WEE1 | P30291 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099658 | 0.81 | NFATC1 (0.43) | MAOAMAOBCHEK1WEE1CDK1 | |
| SCHEMBL16093854 | 0.81 | HSD17B10 (0.33) | MAOAMAOBMAPTTSHRKDM4E | |
| SCHEMBL16093943 | 0.77 | NFATC1 (0.47) | MAOAMAOBCHEK1WEE1KDM4E | |
| SCHEMBL23234240 | 0.72 | ALDH1A1 (0.46) | CNR2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL16099619 | 0.69 | MEN1 (0.36) | CREBBPKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16098685 | 0.68 | CHEK1 (0.40) | CHEK1WEE1CNR2CDK1CCNB1 | |
| SCHEMBL16099686 | 0.68 | NFATC1 (0.41) | CHEK1WEE1CNR2CDK1CCNB1 | |
| SCHEMBL16099077 | 0.68 | SMN1; SMN2 (0.37) | LMNAMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL16123513 | 0.67 | CNR2 (0.41) | CNR2LMNAMAPTTSHRCREBBP | |
| SCHEMBL30939870 | 0.67 | CNR2 (0.41) | CNR2LMNAMAPTTSHRCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |