Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609926 | 0.92 | MAPT (0.37) | MAPTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27856129 | 0.84 | KDM4E (0.39) | MAPTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1609021 | 0.83 | ALDH1A1 (0.42) | MAPTLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1610593 | 0.82 | TUBB4A (0.41) | MAPTLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1609528 | 0.80 | ALPL (0.37) | MAPTLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1609769 | 0.80 | CFTR (0.33) | MAPTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1610481 | 0.80 | CFTR (0.38) | SMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL1610094 | 0.79 | CHRNA7 (0.39) | — | |
| SCHEMBL1609888 | 0.78 | MAPT (0.44) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL11903207 | 0.77 | HSD17B10 (0.36) | MAPTLMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | MAPT 2800/4885LMNA 4805/4885SMN1; SMN2 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.