Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.30 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098616 | 0.85 | ADORA3 (0.32) | ADORA3ADORA2A | |
| SCHEMBL16100006 | 0.76 | ADORA3 (0.41) | ADORA3ADORA2AKDM5ACMA1 | |
| SCHEMBL16097799 | 0.74 | ADORA3 (0.33) | ADORA3ADORA2A | |
| SCHEMBL16099109 | 0.73 | PDE2A (0.33) | — | |
| SCHEMBL16099273 | 0.73 | ADORA3 (0.40) | ADORA3ADORA2AKDM5ACMA1 | |
| SCHEMBL16098699 | 0.70 | ADORA3 (0.44) | ADORA3ADORA2AKDM5ACMA1 | |
| SCHEMBL16100067 | 0.68 | ADORA3 (0.36) | ADORA3ADORA2AKDM5A | |
| SCHEMBL16123634 | 0.67 | DYRK1A (0.40) | RAD52 | |
| SCHEMBL30939985 | 0.67 | DYRK1A (0.40) | RAD52 | |
| SCHEMBL16099174 | 0.67 | HASPIN (0.55) | ADORA3ADORA2AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |