SCHEMBL16100129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2108026	0.85	RXFP1 (0.54)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL22400685	0.82	RXFP1 (0.61)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL18669183	0.80	GAA (0.78)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL9387548	0.79	RAB9A (0.60)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL18669194	0.78	GAA (0.59)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL3024201	0.78	CASP3 (0.58)	RXFP1KDM4EKMT2ACYP1A2CYP3A4
	SCHEMBL6687632	0.78	RXFP1 (0.71)	RXFP1GAAKDM4ERECQLMEN1
	SCHEMBL6940053	0.78	CASP3 (0.58)	RXFP1KDM4ECASP3LMNAALDH1A1
	SCHEMBL6939477	0.78	CASP3 (0.58)	RXFP1KDM4ECASP3LMNAALDH1A1
	SCHEMBL2567485	0.77	RXFP1 (0.55)	RXFP1GAAKDM4ERECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.