Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | ATF4 | P18848 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610062 | 0.81 | PDE2A (0.40) | SLC6A3SMN1; SMN2L3MBTL1KMT2AIDO1 | |
| SCHEMBL1610327 | 0.78 | PDE10A (0.42) | SLC6A3SMN1; SMN2L3MBTL1KMT2ATSHR | |
| SCHEMBL1610223 | 0.78 | NPY1R (0.41) | SMN1; SMN2KMT2ATSHRCYP1A2 | |
| SCHEMBL1609935 | 0.77 | SLC6A3 (0.35) | SLC6A3SMN1; SMN2L3MBTL1RAB9ACNR1 | |
| SCHEMBL1609934 | 0.77 | SLC6A3 (0.35) | SLC6A3SMN1; SMN2L3MBTL1RAB9ACNR1 | |
| SCHEMBL1609147 | 0.76 | PDE10A (0.50) | SLC6A3SMN1; SMN2KMT2ACNR1 | |
| SCHEMBL12712709 | 0.75 | SLC6A3 (0.40) | SLC6A3 | |
| SCHEMBL1611017 | 0.73 | PDE2A (0.38) | SLC6A3KMT2ANPC1RAB9ACYP3A4 | |
| SCHEMBL1610879 | 0.73 | NOS2 (0.38) | SLC6A3KMT2AIDO1 | |
| SCHEMBL1609780 | 0.73 | ADORA2A (0.40) | SLC6A3SMN1; SMN2L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SLC6A3 2437/4885ATF4 1962/4885SMN1; SMN2 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.