Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609696 | 0.82 | P2RX3 (0.38) | ALDH1A1CYP1A2GAAHPGDMAPK1 | |
| SCHEMBL1609147 | 0.79 | PDE10A (0.50) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL1610314 | 0.79 | PDE10A (0.44) | ALDH1A1MAPK1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL1610436 | 0.78 | PDE10A (0.42) | ALDH1A1HPGDMAPK1SMN1; SMN2TSHR | |
| SCHEMBL1610052 | 0.78 | SLC6A3 (0.38) | KMT2ACYP1A2SMN1; SMN2TSHR | |
| SCHEMBL1609853 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAPTSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL1608801 | 0.77 | MTNR1A (0.41) | ALDH1A1MAPK1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL1610298 | 0.76 | SLC6A3 (0.39) | ALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL1609438 | 0.76 | PDE10A (0.42) | KMT2AALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1610899 | 0.76 | PDE10A (0.48) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | NPY1R 3875/4885MEN1 3860/4885KMT2A 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.