Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713186 | 0.88 | DHODH (0.36) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1609557 | 0.85 | CNR2 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL12712701 | 0.85 | CHRM3 (0.41) | SMN1; SMN2ALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL1609736 | 0.84 | PDE10A (0.40) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1609835 | 0.84 | L3MBTL1 (0.36) | SMN1; SMN2ALDH1A1KDM4ELMNAHSP90AA1 | |
| SCHEMBL12738555 | 0.83 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1KDM4ELMNAHSP90AA1 | |
| SCHEMBL1610227 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL1610384 | 0.80 | CHRM3 (0.37) | SMN1; SMN2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL1609980 | 0.80 | CHRM3 (0.43) | SMN1; SMN2ALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL1610011 | 0.79 | TUBB4A (0.42) | SMN1; SMN2HDAC6MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SMN1; SMN2 2654/4885ALDH1A1 1562/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.