Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610082 | 0.81 | ERCC1 (0.34) | PDE10AALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1610086 | 0.80 | PDE10A (0.34) | PDE10AKMT2A | |
| SCHEMBL719721 | 0.79 | PDE10A (0.41) | PDE10AALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1610401 | 0.79 | PDE10A (0.31) | PDE10A | |
| SCHEMBL1609145 | 0.78 | TUBB4A (0.43) | ALDH1A1SMN1; SMN2POLBKDM4EPKM | |
| SCHEMBL1609691 | 0.77 | SLC6A3 (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBKDM4E | |
| SCHEMBL1609767 | 0.77 | TUBB4A (0.42) | ALDH1A1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL1609757 | 0.77 | TUBB4A (0.40) | PDE10AALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1609450 | 0.77 | TUBB4A (0.42) | PDE10AALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1610745 | 0.77 | TRPM8 (0.35) | ALDH1A1SMN1; SMN2LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885ALDH1A1 1562/4885KMT2A 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.