Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102503 | 0.88 | ALDH1A1 (0.36) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16100953 | 0.87 | KDM4E (0.35) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL17499596 | 0.83 | GRIN2D (0.42) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16101075 | 0.82 | HTT (0.39) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL30416262 | 0.78 | NOS3 (0.50) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL6547372 | 0.78 | NOS3 (0.50) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16100316 | 0.78 | NOS3 (0.39) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16105015 | 0.77 | ALDH1A1 (0.38) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16102524 | 0.77 | NOS3 (0.38) | ALDH1A1RAB9ASMN1; SMN2MAPK14NOS3 | |
| SCHEMBL16102108 | 0.75 | NOS3 (0.36) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |