Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629458 | 0.72 | HDAC4 (0.36) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL28260768 | 0.72 | OPRM1 (0.38) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| Phosphine SCHEMBL27942052 | 0.71 | HDAC4 (0.35) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL4599737 | 0.71 | OPRM1 (0.40) | OPRM1OPRK1OPRL1HDAC4MAOB | |
| SCHEMBL28402501 | 0.71 | HDAC4 (0.35) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL6037214 | 0.69 | OPRM1 (0.32) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL20240643 | 0.69 | OPRM1 (0.32) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL11064099 | 0.69 | ALDH1A1 (0.46) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL498014 | 0.69 | OPRM1 (0.50) | OPRM1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL11064104 | 0.69 | ALDH1A1 (0.46) | OPRM1OPRK1OPRL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | OPRM1 3371/4885OPRK1 4705/4885OPRL1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.