Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732379 | 0.81 | NAAA (0.54) | NAAADRD2DRD4DRD3HDAC3 | |
| SCHEMBL4561048 | 0.80 | GGT1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27673425 | 0.79 | CYP26A1 (0.53) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26199837 | 0.79 | CYP26A1 (0.53) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26199653 | 0.77 | NPC1 (0.55) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL31344543 | 0.76 | NAAA (0.48) | NAAADRD2DRD4DRD3HDAC3 | |
| SCHEMBL31344537 | 0.76 | NAAA (0.48) | NAAADRD2DRD4DRD3HDAC3 | |
| SCHEMBL5009820 | 0.75 | MAPT (0.62) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8779817 | 0.75 | HDAC1 (0.79) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29897611 | 0.74 | NPC1 (0.55) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014148929-A1 | METHOD OF ENZYMATIC RESOLUTION OF SERINE RACEMIC DERIVATIVE | PETER-WIRSKI, Maciej (PL) | 2014-09-25 | — | — | WO | claimed |