Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102578 | 1.00 | BCHE (0.64) | BCHEALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28587690 | 0.78 | BCHE (1.00) | BCHEMAPT | |
| SCHEMBL28787615 | 0.75 | BCHE (0.84) | BCHEMAPT | |
| SCHEMBL29728189 | 0.75 | BCHE (0.84) | BCHEMAPT | |
| SCHEMBL28586779 | 0.75 | BCHE (1.00) | BCHE | |
| SCHEMBL28573334 | 0.75 | BCHE (1.00) | BCHE | |
| SCHEMBL28579918 | 0.75 | BCHE (1.00) | BCHEMAPT | |
| SCHEMBL5521696 | 0.75 | KDM4E (0.75) | BCHEKDM4EMAPT | |
| SCHEMBL6720919 | 0.74 | KDM4E (1.00) | BCHEALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28592682 | 0.74 | BCHE (1.00) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2019-02-12 | — | — | US | claimed |
| US-10704076-B2 | Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190127776-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2019-05-02 | — | — | US | disclosed |
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160024551-A1 | MULTI-TIERED, HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014152895-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024551-A1 | MULTI-TIERED, HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | PGLS, GLO1, FDPS | BCHE 1173/4885ALDH1A1 453/4885MEN1 3341/4885 |
| US-20190127776-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | ABCG2, TOE1, TFPI | BCHE 477/4885ALDH1A1 204/4885MEN1 3441/4885 |
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | PGLS, GLO1, FDPS | BCHE 1173/4885ALDH1A1 453/4885MEN1 3341/4885 |
| US-10704076-B2 | Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm | ABCG2, TOE1, TFPI | BCHE 477/4885ALDH1A1 204/4885MEN1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.