Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151621 | 1.00 | MMP2 (0.52) | MMP2SLC1A1GAAKMT2AMEN1 | |
| SCHEMBL10098521 | 0.92 | SLC1A1 (0.51) | MMP2SLC1A1GAAKMT2AMEN1 | |
| SCHEMBL16103221 | 0.92 | SLC1A1 (0.51) | MMP2SLC1A1GAAKMT2AMEN1 | |
| SCHEMBL9275540 | 0.86 | MMP2 (0.64) | MMP2SLC1A1GAAKMT2ASPHK1 | |
| SCHEMBL8526418 | 0.86 | MMP2 (0.64) | MMP2SLC1A1GAAKMT2ASPHK1 | |
| SCHEMBL7272130 | 0.85 | SPHK1 (0.61) | MMP2KMT2ASPHK1L3MBTL1 | |
| SCHEMBL3907033 | 0.85 | MMP2 (0.71) | MMP2SPHK1MMP8EGFRSRC | |
| SCHEMBL8691002 | 0.85 | MMP2 (0.71) | MMP2SPHK1MMP8EGFRSRC | |
| SCHEMBL16150370 | 0.85 | MMP2 (0.56) | MMP2SLC1A1GAAKMT2ASPHK1 | |
| SCHEMBL16150371 | 0.85 | MMP2 (0.56) | MMP2SLC1A1GAAKMT2ASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |