Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615012 | 0.84 | PDE10A (0.49) | KDM4ESMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL121762 | 0.84 | PDE10A (0.49) | KDM4ESMN1; SMN2ALDH1A1PKML3MBTL1 | |
| Hydrochloric Acid SCHEMBL28163034 | 0.83 | PDE10A (0.47) | KDM4ESMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL1609147 | 0.77 | PDE10A (0.50) | KDM4ESMN1; SMN2ALDH1A1SLC6A3PDE4B | |
| SCHEMBL1609979 | 0.75 | PDE4B (0.42) | KDM4ESMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL1610751 | 0.74 | LTC4S (0.42) | KDM4ESMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL1609831 | 0.73 | PDE10A (0.48) | PDE4BPDE4DPDE10A | |
| SCHEMBL1535606 | 0.73 | PDE10A (0.49) | KDM4EALDH1A1PKML3MBTL1MAPK1 | |
| SCHEMBL1609791 | 0.72 | ENPP2 (0.36) | SLC6A3PDE4BPDE4DPDE10ARPS6KB1 | |
| SCHEMBL1610879 | 0.72 | NOS2 (0.38) | P2RX3SLC6A3PDE4BPDE4DPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE8B 2401/4885P2RX3 566/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.