SCHEMBL1611065

SCHEMBL1611065

Cc1ccc2c(c1)c1cnccc1n2-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
FGFR1 P11362 2/20 0.41
CYP19A1 P11511 1/20 0.40
ELANE P08246 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16625774 0.91 ACHE (0.43) ACHEGRIN1GRIN2AKDM4EFGFR1
SCHEMBL12153427 0.90 ACHE (0.40) ACHEGRIN1GRIN2AKDM4EL3MBTL1
SCHEMBL19084854 0.90 ELANE (0.44) ACHEGRIN1GRIN2AKDM4EELANE
SCHEMBL1611018 0.90 KDM4E (0.44) ACHEGRIN1GRIN2AKDM4EL3MBTL1
SCHEMBL22373867 0.90 KDM4E (0.44) ACHEGRIN1GRIN2AKDM4EL3MBTL1
SCHEMBL11965567 0.86 KDM4E (0.46) ACHEKDM4EL3MBTL1ATMFGFR1
SCHEMBL13866625 0.85 ATM (0.56) ACHEKDM4EL3MBTL1ATMFGFR1
SCHEMBL679015 0.85 KDM4E (0.56) ACHEKDM4EL3MBTL1ATMFGFR1
SCHEMBL15945614 0.84 KDM4E (0.44) ACHEKDM4EL3MBTL1ATMFGFR1
SCHEMBL8737061 0.83 ACHE (0.38) ACHEGRIN1GRIN2AKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
EP-3339395-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2018-06-27 EP disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 ACHE 1962/4885GRIN1 355/4885GRIN2A 940/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 ACHE 1962/4885GRIN1 355/4885GRIN2A 940/4885
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 ACHE 298/4885GRIN1 43/4885GRIN2A 167/4885
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND CCNE2, C1S, SCO2 ACHE 2336/4885GRIN1 923/4885GRIN2A 1615/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 ACHE 1962/4885GRIN1 355/4885GRIN2A 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.