Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Gallic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.63 |
| ▸ | CA12 | O43570 | 4/20 | 0.63 |
| ▸ | CA1 | P00915 | 4/20 | 0.63 |
| ▸ | CA7 | P43166 | 4/20 | 0.63 |
| ▸ | CA9 | Q16790 | 4/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | CA4 | P22748 | 3/20 | 0.63 |
| ▸ | CA6 | P23280 | 3/20 | 0.63 |
| ▸ | SELL | P14151 | 3/20 | 0.63 |
| ▸ | SELP | P16109 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CA3 | P07451 | 2/20 | 0.63 |
| ▸ | CA5A | P35218 | 2/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.63 |
| ▸ | SNCA | P37840 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallic Acid SCHEMBL5011532 | 0.92 | CA2 (0.74) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL28275534 | 0.86 | CA12 (0.85) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL16110892 | 0.82 | CA1 (0.62) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL23924977 | 0.81 | CA1 (0.67) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL17105845 | 0.80 | CA12 (0.74) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL28060001 | 0.80 | CA12 (0.90) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL2726519 | 0.80 | CA12 (0.90) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL29282650 | 0.80 | CA12 (0.90) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL27648549 | 0.80 | CA12 (0.90) | CA2CA12CA1CA7CA9 | |
| Gallic Acid SCHEMBL4918056 | 0.79 | CA12 (1.00) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160686-A1 | SOLID FORMS COMPRISING 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PIPERIDINE-2,6-DIONE AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF | CELGENE CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |