Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681622 | 0.84 | ALDH1A1 (0.57) | KMT2AMAPTKDM4EADORA2ALMNA | |
| SCHEMBL20646162 | 0.81 | GPR52 (0.52) | TDP1KMT2ASLC6A2SLC6A3MAPT | |
| SCHEMBL18394893 | 0.78 | TP53 (0.50) | TDP1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL856957 | 0.76 | POLB (0.52) | MAPTKDM4EL3MBTL1ALDH1A1POLB | |
| SCHEMBL5399902 | 0.75 | MAPT (0.50) | TDP1KMT2ASLC6A2SLC6A3MAPT | |
| SCHEMBL5963082 | 0.74 | ALDH1A1 (0.47) | KDM4ELMNAALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL11893514 | 0.74 | POLB (0.50) | MAPTKDM4EL3MBTL1ALDH1A1POLB | |
| SCHEMBL31582366 | 0.73 | TDP1 (0.43) | TDP1KMT2ASLC6A2SLC6A3MAPT | |
| SCHEMBL31582374 | 0.73 | TDP1 (0.43) | TDP1KMT2ASLC6A2SLC6A3MAPT | |
| SCHEMBL10242690 | 0.73 | MAPK1 (0.51) | ALDH1A1POLBMAPK1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159214-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-10-02 | — | — | WO | disclosed |