SCHEMBL16112145

SCHEMBL16112145

COCC(C)(COC)C(=CC(=O)O)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16112144 1.00 KDM4E (0.30) KDM4ETSHR
SCHEMBL8734660 0.81
SCHEMBL889792 0.71 TSHR (0.48) TSHR
Hydrogen Peroxide SCHEMBL28392769 0.71 TSHR (0.33) KDM4ETSHR
SCHEMBL1965967 0.71 TSHR (0.33) KDM4ETSHR
SCHEMBL1965963 0.71 TSHR (0.33) KDM4ETSHR
SCHEMBL3630555 0.71 TSHR (0.33) KDM4ETSHR
SCHEMBL1415787 0.69 TSHR (0.43) KDM4ETSHR
SCHEMBL2855633 0.69 TSHR (0.36) KDM4ETSHR
SCHEMBL2855707 0.69 TSHR (0.36) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926410-B2 Organosiloxane compositions and coatings, manufactured articles, methods and uses DOW CORNING CORPORATION (US) 2018-03-27 US disclosed
EP-2978795-B1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES DOW CORNING (US) 2017-05-31 EP disclosed
US-20160053056-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES DOW SILICONES CORPORATION 2016-02-25 US disclosed
EP-2978795-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES Dow Corning Corporation (US) 2016-02-03 EP disclosed
WO-2014160975-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES DOW CORNING CORPORATION (US) 2014-10-02 WO disclosed