Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855633 | 1.00 | TSHR (0.36) | TSHRALDH1A1KDM4EHMGCRCHRM1 | |
| Acrylamide SCHEMBL9155314 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL1415787 | 0.84 | TSHR (0.43) | TSHRALDH1A1KDM4EHMGCRCHRM1 | |
| SCHEMBL3630555 | 0.81 | TSHR (0.33) | TSHRALDH1A1KDM4E | |
| SCHEMBL1965967 | 0.81 | TSHR (0.33) | TSHRALDH1A1KDM4E | |
| SCHEMBL1965963 | 0.81 | TSHR (0.33) | TSHRALDH1A1KDM4E | |
| Hydrogen Peroxide SCHEMBL28392769 | 0.81 | TSHR (0.33) | TSHRALDH1A1KDM4E | |
| SCHEMBL15546331 | 0.77 | NR4A1 (0.34) | TSHRKDM4E | |
| SCHEMBL15546329 | 0.77 | NR4A1 (0.34) | TSHRKDM4E | |
| SCHEMBL9507054 | 0.73 | FFAR3 (0.33) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877711-A | DURABLE PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | claimed |
| EP-2199333-B1 | Binder-strengthened textile sheet, method for its production and application | JOHNS MANVILLE EUROPE GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2199333-A1 | Binder-strengthened textile sheet, method for its production and application | Johns Manville Europe GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| EP-0611783-B1 | Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0611783-A1 | Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives | CIBA-GEIGY AG (CH) | 1994-08-24 | — | — | EP | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-4877711-A | DURABLE PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |