SCHEMBL2855633

SCHEMBL2855633

CC(O)(O)/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
KDM4E B2RXH2 1/20 0.32
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2855707 1.00 TSHR (0.36) TSHRALDH1A1KDM4EHMGCRCHRM1
Acrylamide SCHEMBL9155314 0.85 ALDH1A1 (0.42) TSHRALDH1A1
SCHEMBL1415787 0.84 TSHR (0.43) TSHRALDH1A1KDM4EHMGCRCHRM1
SCHEMBL3630555 0.81 TSHR (0.33) TSHRALDH1A1KDM4E
SCHEMBL1965967 0.81 TSHR (0.33) TSHRALDH1A1KDM4E
SCHEMBL1965963 0.81 TSHR (0.33) TSHRALDH1A1KDM4E
Hydrogen Peroxide SCHEMBL28392769 0.81 TSHR (0.33) TSHRALDH1A1KDM4E
SCHEMBL15546331 0.77 NR4A1 (0.34) TSHRKDM4E
SCHEMBL15546329 0.77 NR4A1 (0.34) TSHRKDM4E
SCHEMBL9507054 0.73 FFAR3 (0.33) TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804887-B1 POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS STEPAN CO (US) 2017-03-01 EP claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
US-4877711-A DURABLE PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US claimed
EP-2199333-B1 Binder-strengthened textile sheet, method for its production and application JOHNS MANVILLE EUROPE GMBH (DE) 2012-10-24 EP disclosed
EP-2199333-A1 Binder-strengthened textile sheet, method for its production and application Johns Manville Europe GmbH (DE) 2010-06-23 EP disclosed
US-20070043205-A1 Radiation curable thiol-ene composition DSM IP ASSETS B.V. (NL) 2007-02-22 US disclosed
EP-1477511-A1 Radiation curable thiol-ene composition DSM IP Assets B.V. (NL) 2004-11-17 EP disclosed
EP-0611783-B1 Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives CIBA GEIGY AG (CH) 1998-04-01 EP disclosed
EP-0530317-B1 CROSS-LINKED CONDUCTIVE POLYMERS AND ANTISTAT COATINGS EMPLOYING THE SAME EASTMAN KODAK CO (US) 1996-07-31 EP disclosed
US-5376378-A Transdermal drug delivery CIBA-GEIGY CORP. (US) 1994-12-27 US disclosed
EP-0611783-A1 Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives CIBA-GEIGY AG (CH) 1994-08-24 EP disclosed
EP-0530317-A1 CROSS-LINKED CONDUCTIVE POLYMERS AND ANTISTAT COATINGS EMPLOYING THE SAME. EASTMAN KODAK CO (US) 1993-03-10 EP disclosed
US-5126405-A Coatings for photographic films EASTMAN KODAK COMPANY (US) 1992-06-30 US disclosed
EP-0176481-B1 UNSATURATED POLYSILOXANES, POLYMERIZABLE COMPOSITIONS AND CONTACT LENSES THEREFROM CIBA-GEIGY AG (CH) 1991-12-11 EP disclosed
WO-1991018062-A1 CROSS-LINKED CONDUCTIVE POLYMERS AND ANTISTAT COATINGS EMPLOYING THE SAME EASTMAN KODAK COMPANY (US) 1991-11-28 WO disclosed
EP-0285933-B1 USE OF ALKOXYLATED CARBOXYL GROUPS CONTAINING POLYMERISATES IN WASHING AGENTS BASF Aktiengesellschaft (DE) 1990-10-31 EP disclosed
EP-0349810-A2 Process for the preparation of alkoxylated polymers containing carbonyl groups BASF Aktiengesellschaft (DE) 1990-01-10 EP disclosed
EP-0168547-B1 COPOLYMERS FOR WASHING AND CLEANING COMPOSITIONS BASF Aktiengesellschaft (DE) 1989-05-24 EP disclosed
EP-0285933-A1 Use of alkoxylated carboxyl groups containing polymerisates in washing agents BASF Aktiengesellschaft (DE) 1988-10-12 EP disclosed
EP-0176481-A2 Unsaturated polysiloxanes, polymerizable compositions and contact lenses therefrom CIBA-GEIGY AG (CH) 1986-04-02 EP disclosed