SCHEMBL889792

SCHEMBL889792

COCC(C)(COC)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.48
ALDH1A1 P00352 2/20 0.38
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13394353 0.89 TSHR (0.39) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL2708624 0.87 TSHR (0.42) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL9245665 0.87 TSHR (0.42) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL846976 0.87 TSHR (0.38) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL17914298 0.85 CYP2D6 (0.37) TSHRCYP2D6CYP2C19HIF1A
SCHEMBL16715867 0.83 TSHR (0.35) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL27811930 0.80 CYP2D6 (0.37) TSHRCYP2D6CYP2C19HIF1A
SCHEMBL1158850 0.78
SCHEMBL2031592 0.78 DGAT1 (0.42) TSHRCYP2D6CYP2C19HIF1AALDH1A1
SCHEMBL16409145 0.78 GAA (0.37) TSHRCYP2D6CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964224-B1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2024-07-03 EP disclosed
US-11745531-B2 Printing plate precursor, printing plate precursor laminate, method for making printing plate, and printing method FUJIFILM CORPORATION (JP) 2023-09-05 US disclosed
US-11660852-B2 Planographic printing plate precursor, planographic printing plate precursor laminate, plate-making method for planographic printing plate, and planographic printing method FUJIFILM CORPORATION (JP) 2023-05-30 US disclosed
WO-2022262845-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) 2022-12-22 WO disclosed
US-20180149975-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed
US-9974303-B2 Cationic polymers for antimicrobial applications and delivery of bioactive materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-22 US disclosed
US-9879108-B2 Composition, cured film, color filter, laminate, and pigment dispersant FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
US-9855693-B2 Image formation method, decorative sheet, decorative sheet molding, process for producing in-mold molded product, in-mold molded product, and ink set FUJIFILM CORPORATION (JP) 2018-01-02 US disclosed
US-20170288144-A1 ALL SOLID STATE SECONDARY BATTERY, SOLID ELECTROLYTE COMPOSITION USED THEREFOR, ELECTRODE SHEET FOR BATTERY, AND METHOD FOR MANUFACTURING ELECTRODE SHEET FOR BATTERY AND ALL SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2017-10-05 US disclosed
US-9643404-B2 Pigment dispersion composition, inkjet recording method, and method for producing compound FUJIFILM CORPORATION (JP) 2017-05-09 US disclosed
US-7306894-B2 Polymerizable composition, photopolymerizing method and process for producing lithographic printing plate using the polymerizable composition FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
EP-1798218-A1 MONOMER COMPOUND, PROCESS FOR PRODUCING THE SAME, POLYMER THEREOF, AND WATER-BASED CURABLE COMPOSITION KANSAI PAINT CO., LTD. (JP) 2007-06-20 EP disclosed
US-20070072126-A1 Method of producing photosensitive planographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070059643-A1 Method of producing photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-7125877-B2 Benzimidazole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-10-24 US disclosed
EP-1505063-A1 BENZIMIDAZOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-02-09 EP disclosed
US-20040248941-A1 Benzimidazone compound, process for producing the same, and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-12-09 US disclosed
EP-1437352-A1 BENZIMIDAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-07-14 EP disclosed
US-20030236267-A1 Benzimidazole derivatives MSD K.K. (JP) 2003-12-25 US disclosed
EP-0609058-A2 Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1994-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248941-A1 Benzimidazone compound, process for producing the same, and use thereof SI, MLNR, FABP2 TSHR 1588/4885CYP2D6 81/4885CYP2C19 13/4885
US-20030236267-A1 Benzimidazole derivatives OPRL1, GPR119, NPBWR1 TSHR 249/4885CYP2D6 1811/4885CYP2C19 1677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.