Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538480 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRFNTAFNTBKMT2A | |
| SCHEMBL8925736 | 0.82 | TSHR (0.33) | ALDH1A1TSHRFNTAFNTBHPGD | |
| SCHEMBL8925749 | 0.82 | TSHR (0.33) | ALDH1A1TSHRFNTAFNTBHPGD | |
| SCHEMBL3266413 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRFNTAFNTBTHRB | |
| SCHEMBL11329510 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRFNTAFNTBTHRB | |
| SCHEMBL3266415 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRFNTAFNTBTHRB | |
| SCHEMBL6525826 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRFNTAFNTBKMT2A | |
| SCHEMBL6525829 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRFNTAFNTBKMT2A | |
| SCHEMBL16815745 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TSHRKMT2AMEN1HPGD | |
| SCHEMBL82451 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926410-B2 | Organosiloxane compositions and coatings, manufactured articles, methods and uses | DOW CORNING CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| EP-2978795-B1 | ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES | DOW CORNING (US) | 2017-05-31 | — | — | EP | disclosed |
| US-20160053056-A1 | ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES | DOW SILICONES CORPORATION | 2016-02-25 | — | — | US | disclosed |
| EP-2978795-A1 | ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES | Dow Corning Corporation (US) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014160975-A1 | ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES | DOW CORNING CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |