Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111746 | 0.84 | GAA (0.46) | ALDH1A1HTTNR4A2BAZ2BBAZ2A | |
| SCHEMBL16112229 | 0.83 | CCNC (0.40) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL13175846 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTBAZ2BBAZ2AGAA | |
| SCHEMBL25054154 | 0.79 | F2 (0.48) | ALDH1A1HTTNR4A2BAZ2BBAZ2A | |
| SCHEMBL30882487 | 0.79 | F2 (0.48) | ALDH1A1HTTNR4A2BAZ2BBAZ2A | |
| SCHEMBL4140356 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTNR4A2BAZ2BBAZ2A | |
| SCHEMBL16115935 | 0.75 | CCNC (0.71) | ALDH1A1NR4A2BAZ2BBAZ2AGAA | |
| SCHEMBL16116370 | 0.75 | FGFR1 (0.51) | ALDH1A1HTTNR4A2GAACCNC | |
| SCHEMBL14800310 | 0.72 | GABRP (0.49) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL29242478 | 0.72 | MEN1 (0.46) | ALDH1A1HTTBAZ2BBAZ2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159214-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-10-02 | — | — | WO | disclosed |