Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421224 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL1610834 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL130739 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL17261284 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL79575 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL28406 | 1.00 | — | — | |
| SCHEMBL17261285 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL340320 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL1609522 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 | |
| SCHEMBL1612066 | 1.00 | TSHR (0.61) | TSHRTHRBCES2CES1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-09-06 | — | — | US | claimed |
| EP-2476678-A1 | SUBSTITUTED CARBONYL COMPOUNDS | Ube Industries, Ltd. (JP) | 2012-07-18 | — | — | EP | claimed |
| US-11820787-B2 | Benfotiamine derivatives in the treatment of alzheimer's disease | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2023-11-21 | — | — | US | disclosed |
| US-20230263720-A1 | COSMETIC | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-24 | — | — | US | disclosed |
| EP-4151279-A1 | COSMETIC | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-03-22 | — | — | EP | disclosed |
| US-11591354-B2 | Thiamine compound, preparation method and pharmaceutical composition thereof | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2023-02-28 | — | — | US | disclosed |
| CN-109791984-B | Material for photoelectric conversion element for imaging element and photoelectric conversion element containing same | 日本化药株式会社 | 2023-02-07 | — | — | CN | disclosed |
| CN-115551475-A | Cosmetic preparation | 信越化学工业株式会社 | 2022-12-30 | — | — | CN | disclosed |
| US-11374044-B2 | Material for photoelectric conversion element for use in imaging element, and photoelectric conversion element including same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2022-06-28 | — | — | US | disclosed |
| CN-107797382-B | Coloring composition | 住友化学株式会社 | 2022-02-22 | — | — | CN | disclosed |
| EP-3929228-A1 | BATTERY MATERIAL AND ELECTRODE MATERIAL | Nissan Chemical Corporation (JP) | 2021-12-29 | — | — | EP | disclosed |
| US-6306801-B1 | Lubricating oil composition comprising acylated bissuccinimide, zinc dithiophosphate and metallic detergent | NIPPON MITSUBISHI OIL CORPORATION (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-0995789-A2 | Lubricating oil composition | Nippon Mitsubishi Oil Corporation (JP) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999049865-A1 | USE OF PLATELET ACTIVATING FACTOR (PAF) INHIBITORS TO INHIBIT IL-5 INDUCED EOSINOPHIL ACTIVATION OR DEGRANULATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-07 | — | — | WO | disclosed |
| EP-0103877-B1 | PHOSPHATE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
| EP-0071892-B1 | PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | disclosed |
| US-4481196-A | ANTI-FIBROSARCOMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-06 | — | — | US | disclosed |
| EP-0103877-A1 | Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-28 | — | — | EP | disclosed |
| EP-0089635-A2 | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-28 | — | — | EP | disclosed |
| EP-0071892-A2 | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591354-B2 | Thiamine compound, preparation method and pharmaceutical composition thereof | SLC19A2, APP, BACE1 | TSHR 553/4885THRB 112/4885CES2 4120/4885 |
| US-11820787-B2 | Benfotiamine derivatives in the treatment of alzheimer's disease | PSEN2, PSEN1, SLC18A2 | TSHR 2327/4885THRB 3586/4885CES2 727/4885 |
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | PTGER2, PTGER1, LTB4R2 | TSHR 2206/4885THRB 1586/4885CES2 1304/4885 |
| US-11374044-B2 | Material for photoelectric conversion element for use in imaging element, and photoelectric conversion element including same | SLC19A1, SLC46A1, SLC19A2 | TSHR 4479/4885THRB 4537/4885CES2 1333/4885 |
| US-20230263720-A1 | COSMETIC | ALG1, ALG3, CUTA | TSHR 2924/4885THRB 1935/4885CES2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.