Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851561 | 0.86 | RAB9A (0.57) | ALDH1A1RAB9ANPC1MAOBHPGD | |
| SCHEMBL7632516 | 0.84 | KDM4E (0.50) | ALDH1A1RAB9ANPC1MAOBHPGD | |
| SCHEMBL13883595 | 0.83 | RAB9A (0.49) | ALDH1A1RAB9ANPC1MAOBHPGD | |
| SCHEMBL16115976 | 0.83 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL7625691 | 0.80 | LMNA (0.50) | RAB9ANPC1MAOBHPGDCYP1A2 | |
| SCHEMBL12578373 | 0.78 | SMN1; SMN2 (0.64) | ALDH1A1RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL30665865 | 0.78 | LMNA (0.55) | ALDH1A1HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL26654446 | 0.78 | LMNA (0.55) | ALDH1A1HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL286726 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL13889404 | 0.76 | MAOB (0.48) | ALDH1A1RAB9ANPC1MAOBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978754-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978747-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |