Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495116 | 0.86 | MAPT (0.46) | NPSR1ALDH1A1CACNA1BNR1I2POLB | |
| SCHEMBL16068871 | 0.81 | NPSR1 (0.50) | NPSR1CES2ALDH1A1HPGDGPR35 | |
| SCHEMBL8848783 | 0.78 | KDM4E (0.49) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| SCHEMBL15898966 | 0.78 | NPSR1 (0.50) | NPSR1CES2ALDH1A1HPGDGPR35 | |
| SCHEMBL2228176 | 0.77 | ALDH1A1 (0.60) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| SCHEMBL30889519 | 0.77 | ALDH1A1 (0.60) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| SCHEMBL29123913 | 0.76 | CFTR (0.61) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| SCHEMBL31374385 | 0.76 | ALDH1A1 (0.46) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| Hydrochloric Acid SCHEMBL8492943 | 0.76 | ALDH1A1 (0.58) | CES2ALDH1A1HPGDCACNA1BNR1I2 | |
| SCHEMBL17080315 | 0.76 | KDM4E (0.50) | CES2ALDH1A1HPGDCACNA1BNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014154829-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-10-02 | — | — | WO | disclosed |