Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146258 | 0.85 | KDM4E (0.62) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL29502160 | 0.85 | KDM4E (0.62) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL2855495 | 0.81 | KDM4E (0.55) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11615858 | 0.81 | ALDH1A1 (0.46) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL3481145 | 0.81 | HPGD (0.58) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL28025037 | 0.79 | SMN1; SMN2 (0.51) | NPC1MEN1KMT2ACYP2D6MAPT | |
| SCHEMBL29694578 | 0.79 | SMN1; SMN2 (0.61) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL1986986 | 0.79 | ALDH1A1 (0.61) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11694926 | 0.79 | SMN1; SMN2 (0.61) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL27836782 | 0.79 | KMT2A (0.60) | NPC1RAB9AMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152013-A1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-09-25 | — | — | WO | disclosed |