Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611866 | 1.00 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL12713074 | 0.91 | PDE10A (0.35) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL1610775 | 0.91 | PDE10A (0.35) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL1610312 | 0.91 | PDE10A (0.35) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL1609935 | 0.89 | SLC6A3 (0.35) | RAB9ASMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL1609934 | 0.89 | SLC6A3 (0.35) | RAB9ASMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL1610320 | 0.86 | ALDH1A1 (0.33) | RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL1610318 | 0.86 | ALDH1A1 (0.33) | RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL1610213 | 0.85 | SLC6A3 (0.37) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL1610209 | 0.85 | SLC6A3 (0.37) | NPC1RAB9ASMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | NPC1 3897/4885RAB9A 3012/4885SMN1; SMN2 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.